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RNA

35 articles

RNA interference as a precision therapeutic platform for Parkinson’s disease: from molecular mechanisms to translational challenges science Protein-building RNA molecules reveal possible remnants of an ancestral genetic code science All 5 genetic “letters” of DNA and RNA discovered in a 4.5-billion-year-old asteroid science RNA-protein interactions could lead to new coronavirus drug targets science A proof-of-concept test can spot bladder cancer in urine jurnal A protein that regulates mRNA decoding can itself be regulated with implications for understanding cancer science RNA archiving method reveals what a cell did days ago science Researchers improve RNA extraction from precision-cut lung slices science RNA processing factors are associated with microglial heterogeneity and intercellular communication in ischemic stroke science Molecular functions, cellular responses and pathological implications of the RNA modification N6-methyladenosine science Two-in-one tool tracks viral RNA inside live infected cells in real time science Too much RNA can starve cells of energy, scientists discover science 'Raman barcodes' distinguish 20 SARS-CoV-2 variants by their RNA architecture science Natural RNA modifications in archaea mirror those used in medicine science A small RNA switch with huge potential opens up new possibilities for synthetic biology science Random mutations turn RNA droplets into cell-like structures that move and store cargo science Author Correction: Nuclear condensates formed by truncated mutant NEK1s impede ribosomal RNA biogenesis and drive motor dysfunction science Nanoneedle arrays map RNA in fresh tissue without sequencing or amplification science Automated lipid nanoparticle production could accelerate the development of RNA therapies science New formulation helps RNA vaccines withstand high temperatures health Modification of magnetic nanoparticles improves RNA isolation science Circular mRNA helps cell factories make up to six times as much protein science Under stress, bacterial RNA and proteins tell different stories science RNA 'delivery tags' guide key messages to distant neuron branches science How one RNA nucleotide switch activates fluorescent dyes science PQBP1-dependent alternative RNA splicing underlies high calorie diet-induced cognitive impairment science Virus-like particles enable gene activity tracking over time in the same cells science Spatial transcriptomics reveals laminar and cell-type-specific A-to-I RNA editing signatures in the macaque cortex science AI-designed proteins enable a new generation of RNA transporters science New model explains how bacterial promoter elements set gene activity and regulation science Algorithm improves detection of differentially expressed genes in large single-cell trajectory data sets science A Google-like search engine for single-cell RNA data could answer previously impossible questions science RNA droplets may have helped start life on Earth science Too much RNA can starve cells of energy, study finds science New lipid nanoparticle delivers capped circular RNA for longer-lasting gene expression science