The NFL is set to put a bow on the first month of the regular season when they roll out the Week 4 slate. For those clubs that are 0-3 and possibly even 1-2 coming into the weekend, these contests could make-or-break their hopes of pushing for the playoffs. If those stakes weren't high enough, four pivotal divisional games are on the docket, including Steelers-Browns on Thursday and Falcons-Saints on Monday.
Another divisional matchup is Kansas City vs. Las Vegas, two of the five teams coming out of Sunday's action that are 3-0 on the year. One of their undefeated streaks will come to a close on Sunday, and the oddsmakers believe it'll be the Raiders, who are home dogs in that AFC West matchup.
Of course, the odds only indicate what is likely to happen, so the Raiders (and others) can look to defy them in Week 4. With that said, let's take our first look at the Week 4 odds and see who the oddsmakers have favored as the 2026 season keeps chugging along. All lines via DraftKings; all games on Sunday unless noted While it's not surprising to see Pittsburgh entering Week 4 at 2-1, it is surprising to see Cleveland with the same record.
They've logged back-to-back wins under Deshaun Watson, and the Browns quarterback has looked sharp over that stretch. That could be why the line for this game has dipped from Steelers -3 at the open to Steelers -2.5, falling below that key field-goal threshold. Both Pittsburgh and Cleveland are 2-1 ATS this season as well, but the Steelers' lone ATS loss did come on the road.
The NFL heads to Tottenham Hotspur Stadium for this matchup. On this neutral site, the Colts have ticked down from a 4.5-point favorite at the open to a 3.5-point favorite. That slight movement toward Washington could be thanks to a flip of optimism around the offense in the wake of Jayden Daniels (elbow) going down.
In his first start of the season, backup Marcus Mariota put together a strong performance against Seattle, throwing for three touchdowns. With that in mind, the Over could be in play here, as it's 3-0 in Commanders games this season and 2-1 in Colts games. The Giants edged out a hard-nosed win over the Titans in Week 3.
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