No. 7 Alabama continued its dominant run with a 49-18 win against South Carolina in Week 4, with sophomore quarterback Keelon Russell throwing for 365 yards. The Crimson Tide (4-0, 2-0 SEC) now head to Starkville for a marquee clash against another unbeaten in Mississippi State. The Bulldogs (4-0, 2-0 SEC) are ranked No. 16 nationally and have been impressive in their own right, most recently holding off Missouri 31-24 last week.
MSU quarterback Kamario Taylor and Russell are third and fourth in the 2026 Heisman Trophy odds at +750 and +1100, respectively. Claim the latest Polymarket promo code CBSSPORTS to get a $25 bonus after depositing $10: Kickoff is set for noon ET at Davis Wade Stadium in Starkville, Mississippi. Alabama is the 5.5-point favorite in the latest Alabama vs.
Mississippi State odds, while the over/under is 61.5 points. Before making any Alabama vs. Mississippi State picks, check out the Alabama vs.
Mississippi State predictions from the SportsLine Projection Model. Mississippi State over/under Alabama vs. Mississippi State money line Alabama vs.
Mississippi State streaming New to sports trading? Visit our Kalshi promo code review and get a $55 bonus after $25+ in trades with the Kalshi promo code CBSSPORTS55: After simulating Alabama vs. Mississippi State 10,000 times, SportsLine model is going Over 61.5 points at betting apps.
These teams have been lighting up the scoreboard at a faster pace than oddsmakers have expected this year. A combined seven of their eight games have cleared the total. The one exception was Mississippi State's game against Missouri last week, which fell just 3.5 points shy of the total.
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