The Los Angeles Chargers will look to get into the win column for the first time this season when they battle the undefeated Kansas City Chiefs in a key AFC West matchup on Sunday afternoon. Los Angeles is coming off a 23-17 loss against the Denver Broncos last Sunday, while Kansas City is coming off its bye following a 30-27 win over the Las Vegas Raiders on Oct. 4. The Chargers (0-5), off to their worst start since 2000 when they were 0-11, are 0-3 against AFC foes.
The Chiefs (4-0), who missed the playoffs for the first time in 10 years, are 2-0 on their home field in 2026. Visit our Kalshi promo code review and get a $55 bonus after $25+ in trades with the Kalshi promo code CBSSPORTS55: Kickoff is set for 4:25 p.m. ET on CBS and Paramount+ from GEHA Field at Arrowhead Stadium in Kansas City, Mo.
Chargers odds have Kansas City as a 7.5-point favorites. The over/under for total points scored is 41.5. Before making any Chargers vs.
Chiefs picks, be sure to see the Chargers vs. Chiefs predictions from SportsLine's proven model. The model, which simulates every NFL game 10,000 times, is up more than $5,000 for $100 players on betting sites on top-rated NFL picks since its inception.
The model entered Week 6 of the 2026 NFL season on a 57-46 run on top-rated picks dating back to 2024. Anybody following its picks at NFL betting sites could have seen strong returns. Now, the model has zoned in on Chargers vs.
You can head to SportsLine now to see its picks. Here are several NFL odds and betting lines for Chiefs vs. Chargers: Claim the latest Polymarket promo code CBSSPORTS to get a $25 bonus after depositing $10: After 10,000 simulations of Chargers vs.
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