This raises the question of whether there are common changes in neural activity that occur during transitions between wakefulness and anesthesia. A landmark study by Luppi and colleagues now reveals a conserved dynamic signature of anesthesia that spans hundreds of millions of years of evolution. This is a preview of subscription content, access via your institution Access Nature and 54 other Nature Portfolio journals Get Nature+, our best-value online-access subscription Receive 12 print issues and online access Prices may be subject to local taxes which are calculated during checkout Kelz, M.
Biol. 29, R1199–R1210 (2019). Article CAS PubMed PubMed Central Google Scholar Luppi, A. Neurosci. https://doi.org/10.1038/s41593-026-02460-4 (2026).
Neuron 112, 1553–1567 (2024). Conscious Cogn. 10, 165–183 (2001). Anesthesiology 118, 1264–1275 (2013).
Anesthesiology 129, 942–958 (2018). Cell Reports 45, 117048 (2026). A., Roelfsema, P., Changeux, J.-P. & Dehaene, S.
Neuron 105, 776–798 (2020). Biol. 19, e1011465 (2023). USA 109, E3377–E3386 (2012).
Huang, Z., Liu, X., Mashour, G. Neurosci. 38, 2304–2317 (2018). Anaesth. 132, 300–311 (2024).
Extract — continue reading at the source.
