The New York Giants will look to continue their strong start to the season when they take on the Los Angeles Rams on 'Monday Night Football.' New York is coming off a 28-20 win over the Dallas Cowboys, while Los Angeles dropped a 27-7 decision to the San Francisco 49ers in Melbourne, Australia. Aaron Donald is set to make his return to the Rams after sitting out the opener, though Los Angeles is without Myles Garrett, who went on the IR this week with a knee injury. Puka Nacua (hip) is questionable for L.A, while his backup, Jordan Whittington (quad is doubtful).
Claim the latest Polymarket promo code CBSSPORTS to get a $50 bonus after $10 in trades: Kickoff is set for 8:15 p.m. ET from SoFi Stadium in Inglewood, Calif. Rams odds have Los Angeles as a 6.5-point favorite, while the over/under for total points scored is 47.5.
Before making any Rams vs. Giants picks or 2026 NFL Week 2 predictions, be sure to see what the SportsLine projection model has to say. The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on betting sites on top-rated NFL picks since its inception.
The model enters Week 2 of the 2026 NFL season on a 53-39 run on top-rated picks dating back to 2024. Anybody following its picks at NFL betting sites could have seen strong returns. Now, the model has zoned in on Giants vs.
You can head to SportsLine now to see its picks. Here are several NFL odds and betting lines for Rams vs. Giants: New to sports trading?
Visit our Kalshi promo code review and get a $55 bonus after $25+ in trades with the Kalshi promo code CBSSPORTS55: After 10,000 simulations of Giants vs. Rams, the model is going Over 47.5 points at betting apps. The Over has hit in five of the last eight head-to-head meetings between the Giants and Rams, including one push.
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