Hundreds of thousands of women die from complications related to pregnancy and childbirth every year, with the burden falling overwhelmingly on poorer countries and as hard-won progress has slowed amid cuts to international aid. A hidden factor driving these deaths is anaemia, a critical but overlooked contributor to severe postpartum haemorrhage (PPH), according to research from trials released earlier this year by the London School of Hygiene and Tropical Medicine. To win tickets to see Bel Trew’s latest compelling documentary click here PPH is the leading cause of maternal death globally and anaemia could be responsible for half of severe cases in sub-Saharan Africa and South Asia, researchers found.
Yet the deficiency receives relatively little attention in guidelines or public health programmes and, for decades, the main nutritional intervention has been the same: iron and folic acid tablets. There are six types of nutritional anaemia, though, according to Dr Martin Mwangi, lead of the Healthy Mothers Healthy Babies programme at the Micronutrient Forum, meaning governments have been focused only on the iron-deficiency part or a broader problem and anaemia rates have barely changed. The solution, many health experts believe, is multiple micronutrient supplements, or MMS, which contain iron and folic acid, as well as 13 other vitamins and minerals.
While there have been no studies on its impact on maternal mortality, modelling across 25 low- and middle-income countries published in the British Medical Journal in May estimated that replacing iron and folic acid with MMS could prevent 3.5 million low-birthweight births and 186,000 stillbirths over five years. MMS in pregnancy also reduces maternal anaemiaat term by 12 per cent compared to iron and folic acid alone, according to the World Health Organisation. Other studies show that MMS helps prevent births of small newborns at highest risk for infant mortality.
It may also reduce childhood stunting that last until adulthood, and separate research published this week in Brain Communications also pointed to a correlation between anaemia during pregnancy and smaller brain volume in babies, with movement and learning affected. Organisations like the Micronutrient Forum advocate for the widespread adoption of MMS for “its tremendous benefits for the women of the world”, Dr Mwangi says. Providing full-pregnancy MMS often costs as little as $2 (£1.50) per woman and yields massive health and economic benefits in terms of the cost of lives saved and other factors.
Although MMS has been around since the 1990s, improvements to medical technology and manufacturing have dramatically reduced costs and governments are starting to adopt it. In May, ministers from Sierra Leone, Rwanda, Nigeria and Pakistan committed to integrating MMS into their national antenatal systems, and more than 30 others are also looking into or trialing the supplement. A woman dies in childbirth globally almost every two minutes, with Sub-Saharan Africa accounting for more than two thirds of the estimated 260,000 deaths a year.
More than 90 per cent of maternal deaths occur in low- and lower-middle-income countries. Hard Labour: Inside the global crisis killing mothers and babies, a documentary for Independent TV, revealed how hard won gains in maternal mortality were being reversed in some of the hardest places on earth to give birth. Severe anaemia can increase the risk of PPH, infection and fatigue.
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