A study imputes fluid intelligence from correlated variables to expand the UK Biobank analysis sample from around 285,000 to 455,000 individuals, boosting discovery of both common and rare genetic variants and charting a roadmap for imputing phenotypes while minimizing bias in future gene-discovery studies. This is a preview of subscription content, access via your institution Access Nature and 54 other Nature Portfolio journals Get Nature+, our best-value online-access subscription Receive 12 print issues and online access Prices may be subject to local taxes which are calculated during checkout Okbay, A. et al. Genet. 54, 437–449 (2022).
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