The 11th-ranked Oklahoma Sooners battle the Michigan Wolverines in a key matchup between SEC and Big Ten behemoths. Oklahoma is coming off a 51-0 thrashing of UTEP in Week 1, while Michigan won on a controversial Hail Mary in a 13-12 triumph over Western Michigan. The Sooners (1-0), who finished 6-2 and tied for fifth in the SEC last season, were 10-3 overall in 2025.The Wolverines (1-0), who tied for fourth in the Big Ten at 7-2, were 9-4 overall last season.
Claim the latest Polymarket promo code CBSSPORTS to get a $50 bonus after $10 in trades: Kickoff is set for noon ET from Michigan Stadium in Ann Arbor, Mich. The Sooners are 4.5-point favorites in the latest Oklahoma vs. The over/under for total points is 43.5.
Oklahoma leads the all-time series 2-0, including a 24-13 win in Norman last year. Before making any Michigan vs. Oklahoma picks, check out what SportsLine college football expert Mike Tierney has to say.
Tierney is a veteran sportswriter and handicapper. Over the past two college football seasons, Tierney is 121-103 on college football betting sites. He's also 15-7 (+718) on his last 22 picks involving Michigan, returning $741 to $100 players on betting sites.
Anyone following could have seen huge returns. Now, Tierney has locked in another confident pick for Oklahoma vs. You can visit SportsLine now to see his picks.
Here are the FBS college football odds and trends for Michigan vs. Oklahoma: New to sports trading? Visit our Kalshi promo code review and get a $25 bonus after $25+ in trades with the Kalshi promo code CBSSPORTS: One of Tierney's top picks for Oklahoma vs.
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