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Missouri vs. Kansas odds, picks, predictions: Betting preview, start time for Week 2 college football matchup

Missouri vs. Kansas odds, picks, predictions: Betting preview, start time for Week 2 college football matchup

cbssports.com 11.09.2026 14:10 11 views
The Border War between Missouri and Kansas takes place in Week 2 in Lawrence

After a 14-year hiatus, the Border War returned in 2025 with the Missouri Tigers defeating the Kansas Jayhawks 42-31 in Columbia. This year, the Border War shifts to Lawrence, where the Jayhawks will be at home. Both the Tigers and Jayhawks won comfortably in Week 1 of the 2026 college football season against overmatched opponents, so this will be the first true test for two programs trending in opposite directions.

Kickoff for this prime-time affair on Friday, Sept. 11 is set for 8 p.m. Kansas at DraftKings and get $200 in bonus bets when you spend $5+: Eli Drinkwitz has a new quarterback in tow, as Ole Miss transfer Austin Simmons takes the reins for the No. 23 Tigers. He was impressive in his Mizzou debut, throwing for 252 yards and four touchdowns in the first half before being taken out for the rest of the contest.

Donovan Olugbode, the Tigers' top holdover at receiver, had 107 yards and two scores. Lance Leipold enters his sixth season at Kansas, and after a nine-win season in 2023, he's failed to reach bowl eligibility in each of the last two seasons. Before making your wagers on Missouri vs.

Kansas on Friday, take a look at what the SportsLine Projection Model is saying about this matchup. The model simulates every FBS game 10,000 times. It is on a 33-20 run on top-rated CFB money-line picks on betting sites since the 2024 season, and it has been upgraded for the 2026 season to even better factor in the transfer portal.

Anybody following its picks on college football betting sites could have seen strong returns. Mizzou's 29 wins over the last three seasons, including two bowl wins, rank fifth among SEC programs, with only Georgia, Texas, Ole Miss and Alabama winning more. Drinkwitz has registered two double-digit win campaigns in the last three years, but things unraveled in 2025 after a 5-0 start.

Part of that opening surge was a win over Kansas in Columbia, highlighted by Brett Norfleet's two touchdowns and Jamal Roberts' game-sealing 63-yard touchdown run. Both Norfleet and Roberts are back for 2026, but Mizzou is still going to be without top running back Ahmad Hardy. Hardy is recovering from a gunshot injury he suffered in the offseason, and while he's cleared to practice, Drinkwitz has said he needs to see sustained work in order for the star to participate in a game.

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