One of the oldest rivalries in college football resumes as the Kansas Jayhawks host the Missouri Tigers in a Friday night Week 2 college football matchup. The two rivals first faced off in 1891 and after a 14-season hiatus following Mizzou's departure to the SEC, the teams resumed the rivalry last year, a game Missouri won 42-31. Each team poured in the offense in Week 1 routs.
This game will offer a stiffer challenge. Visit our DraftKings promo code review and get $200 in bonus bets as a new user after $5+ in wagers here: Kickoff is at 8 p.m. ET from Kansas Memorial Stadium in Lawrence, Kan.
The Tigers are 5.5-point favorites in the latest Missouri vs. Kansas odds, while the over/under is 51.5 points. Before making any Kansas vs.
Missouri picks, check out the Missouri vs. Kansas predictions from the SportsLine Projection Model. The model simulates every FBS game 10,000 times.
It is on a 33-20 run on top-rated CFB money-line picks on betting sites since the 2024 season, and it has been upgraded for the 2026 season to even better factor in the transfer portal. Anybody following its college football betting picks could have seen strong returns. Now, the model has set its sights on Missouri vs.
You can visit SportsLine now to see the picks. Here are the FBS college football odds and trends for Kansas vs. Missouri: New to sports trading?
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