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NFL Week 5 early odds: Bears favorites at Lambeau, Bills underdogs to Rams

NFL Week 5 early odds: Bears favorites at Lambeau, Bills underdogs to Rams

cbssports.com 05.10.2026 14:01 7 views
Los Angeles is a slight favorite against Buffalo in a potential Super Bowl preview, while Chicago enters Lambeau Field favored over Green Bay

Now that the first month of the season is in the books, it's time for the true contenders to begin separating themselves from the pack. That could happen as soon as Week 5, as there are several high-profile matchups on the docket. Once again, Sunday's action starts a little early with the Eagles and Jaguars playing in London.

Jacksonville travels to its home away from home as a favorite, while Philly will look to get its offense back on track after collapsing against the Rams in Week 4. After that, we have five divisional matchups, including Bears-Packers, with Chicago entering Lambeau Field as a road favorite. We then wrap up the entire slate on Monday for what could be a Super Bowl preview between the Bills and Rams from SoFi Stadium, so this slate packs quite the punch.

As we begin to turn our attention to Week 5, let's jump into the odds and see who the oddsmakers have coming out on top and which games could be high-scoring affairs. Note: Kansas City and Carolina are on the bye in Week 5 All lines via DraftKings; all games on Sunday unless noted Dallas is now a double-digit favorite over the Buccaneers, laying 10 points after the line initially opened at Coboys -9.5. This comes after we got our first glimpse of Jalon Daniels for Tampa Bay, and the undrafted rookie quarterback managed just two scoring drives in a loss to Green Bay.

With Baker Mayfield still out, the Cowboys are rightfully being looked at as a heavy favorite, and they are riding high after a road win in Houston. Dallas is 3-1 ATS this season, including a cover in their home opener. The Bucs are 0-4 ATS through the first month.

Jacksonville has jumped out to a 4.5-point favorite over the Eagles, which is up from the 3-point spread they were laying at the open. The Jaguars are one of the more underrated teams in the NFL through the first three weeks, owning a 3-1 SU and ATS record with an average margin of victory of 12.8 points (second-highest in the NFL). They take on an Eagles team that has been banged up with injuries and saw Saquon Barkley leave Sunday's loss to the Rams with a hamstring injury.

So far, the Eagles are 0-4 ATS. Because of the questions surrounding Philadelphia's offense, the total has dropped from 44.5 to 43.5. Chicago opened as a 1.5-point road favorite over the Packers and that has since bumped up to -2.5.

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