Just when you think you have everything pegged, the league will rip the carpet right out from under you before you even realize it. On a week-to-week basis, any team appears capable of winning, no matter how bleak things may seem from the outside looking in. Take the Cardinals-Rams games for instance.
Los Angeles was dubbed a superteam coming into 2026 and the prohibitive favorite to win the Super Bowl. All the while, Arizona was pinpointed as one of the worst teams in the league and possibly earmarked for the No. 1 overall pick. The Cardinals rolled into SoFi Stadium and handed us arguably the biggest upset of the season.
The only thing that stung about Arizona's stunning victory was that we didn't highlight it in last week's post. I had the Cardinals coverering in my weekly picks column, but that was thinking more along the lines of hitting the backdoor cover late. While we weren't able to sniff out that upset, we did put you on to the Texans taking down the Jaguars in London and the Tennessee Titans taking down the Colts in Indy in last week's piece.
We nearly had the Bucs as we win as well, but they couldn't outlast the Steelers in overtime. That's enough looking back at Week 6. Now, it's time to set our sights on Week 7 and identify a handful of favorites that are officially on upset alert.
Not only are they 2-4 to begin the season and in last place in the NFC West, but the injury bug is starting to take massive bites out of the roster. Following the loss to Arizona, head coach Sean McVay announced that star receiver Davante Adams ruptured his hamstring and is out for 6 to 10 weeks. On top of that, newly signed kicker Blake Grupe tore his ACL and is out for the year, as is defensive tackle Poona Ford (ruptured triceps).
Fellow defensive tackle Kobie Turner is also going to miss at least a month with a groin injury. And that's not even mentioning Myles Garrett (knee), who is still sidelined. That is a lot of bodies piling up for the Rams, which -- as we started to see last week -- makes them vulnerable to just about any club.
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