The fourth-ranked Ole Miss Rebels will battle the 21st-ranked Florida Gators in a key SEC matchup on Saturday afternoon. Mississippi is coming off an emotional 32-24 win over LSU and their former coach Lane Kiffin, while Florida outlasted Auburn 44-39 last Saturday. The Rebels (3-0, 1-0 SEC), who are 2-0 against ranked opponents, are playing their first road game of the season.
The Gators (3-0, 1-0 SEC), who are 2-0 on their home field in 2026, are playing against their first ranked opponent this year. The all-time series is tied 13-13-1. Ole Miss won last year's meeting 34-24.
Claim the latest Polymarket promo code CBSSPORTS to get a $50 bonus after $10 in trades: Kickoff is set for 3:30 p.m. ET at Florida Field at Ben Hill Griffin Stadium in Gainesville, Fla. The Gators are 3.5-point favorites in the latest Florida vs.
The over/under for total points is 58.5. Before making any Ole Miss vs. Florida picks, check out the Ole Miss vs.
Florida predictions from the SportsLine Projection Model. The model simulates every FBS game 10,000 times. It is off to a profitable 22-19 start on all top-rated college football picks at betting sites so far this season, and it has been upgraded for the 2026 season to better factor in the transfer portal.
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