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Steelers vs. Patriots picks, odds: Betting preview, prediction, start time and more for NFL Week 2 showdown

Steelers vs. Patriots picks, odds: Betting preview, prediction, start time and more for NFL Week 2 showdown

cbssports.com 20.09.2026 18:01 2 views
A pair of AFC playoff hopefuls square off as the Patriots host the Steelers on Sunday, and we have all the NFL betting tips you need

The New England Patriots are hoping to bounce back from a difficult opener when they host the Pittsburgh Steelers at Gillette Stadium for an NFL Week 2 matchup Sunday. The Patriots kicked off the 2026 NFL season with a Super Bowl rematch on the road against the Seahawks last Wednesday, and the AFC champions lost 13-10. Now, they'll face a Pittsburgh team that opened its season with a 20-13 victory against the Falcons last Sunday.

Kickoff for the Week 2 matchup is set for 1 p.m ET. Bet on Steelers-Patriots and NFL Week 2 with the latest FanDuel promo code here and get $350 in bonus bets: New England is listed as a 5.5-point favorite in the latest NFL odds from FanDuel Sportsbook, while the Over/Under for total points scored is set at 41.5. The Patriots went 14-3 in the regular season last year and lost 29-13 in the Super Bowl, while the Steelers won the AFC North at 10-7 but lost to the Texans 30-6 in the Wild Card Round.

Fans who want to try NFL betting on games like Steelers vs. Patriots at the best betting apps need to see our picks for this matchup. And be sure to check out what SportsLine experts and the SportsLine Projection Model have to say.

Get $200 in bonus bets when you spend $5+ at DraftKings: New England is surely smarting from another setback to Seattle, but Mike Vrabel and Co. know they have the team to get back to the Super Bowl. The Patriots went 14-3 last season and went into the playoffs as the No. 2 seed behind Denver. The Pats caught a break when Broncos QB Bo Nix was injured before the AFC Championship Game and gutted out a 10-7 victory in brutal winter conditions.

New England quarterback Drake Maye finished second in MVP voting in his second season in the NFL, as he threw for 4,394 yards (fourth in NFL) and 31 touchdowns (third). The offensive line has been an issue -- Maye was sacked six times in the Super Bowl -- and top offseason addition A..J Brown will be out for about six weeks with a high ankle sprain. Still, the Pats matched Seattle almost yard for yard in Week 1, but Maye was harassed into three interceptions and was sacked three times in the fourth quarter.

Maye did rush for 47 yards, with Rhamondre Stevenson rushing for a team-high 51 and adding 44 receiving yards. Running back TreVeyon Henderson, who posted 1,132 total yards in 2025, returned to practice Monday and is questionable to suit up Sunday. DeMario Douglas (five receptions), Hunter Henry (three for 26 yards) and Mack Hollins (four for 51) all stepped up after Brown went down.

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