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Parkinson

60 articles
RNA interference as a precision therapeutic platform for Parkinson’s disease: from molecular mechanisms to translational challenges science Computer vision-derived gait-state tracking of acute treatment response in Parkinson’s disease: external and prospective validation science Cortical proteomic alterations and exploratory glycopeptide profiling of the frontal cortex of Parkinson's disease science Transcranial alternating current stimulation for Parkinson's disease: a systematic review and meta-analysis of motor outcomes science Circulating branched-chain amino acids and multimodal signatures of incident Parkinson's disease: a prospective cohort study science Parkinson’s may be driven by ‘vicious cycle’ that disrupts brain waste drainage science NAD+ precursor fails in Parkinson’s disease science Choroid plexus enlargement as an imaging correlate of cognitive impairment in Parkinson’s disease: a normative brain-charts analysis science Sex-dependent associations among peripheral inflammation, glymphatic system-related imaging markers, and cognitive and motor manifestations in Parkinson’s disease science Progress accelerates in Parkinson’s treatments science Replacing the neurons that Parkinson’s destroys science Parkinson’s: beyond the brain science How a once-controversial idea is advancing understanding of Parkinson’s disease science Six highlights from Parkinson’s disease research science Fine-tuning brain stimulation to fight Parkinson’s disease science Precision prediction of motor fluctuations in advanced Parkinson’s disease via multiregional neural sensing science Clearing the way for a transformative stem-cell treatment for Parkinson’s disease science How the brain protects itself from Parkinson’s disease science Oculomotor and clinical correlates with impaired optokinetic nystagmus in Parkinson’s disease science Could chemicals contribute to Parkinson’s? science Non-invasive oral magnetoelectric vagus nerve neuromodulation for Parkinson’s disease therapy science The brain lymphatic drainage system: structure, physiological functions, and pathological involvement in Parkinson’s disease science Mapping symptom domains and laterality to substantia nigra subregions in early Parkinson’s disease using neuromelanin MRI science Brain-first body-first model translated to individual-level characterization in Parkinson’s disease: multimodal imaging and clinical approach science Sniffing out the link between odor and disease jurnal Beyond dopamine: the role of non-dopaminergic systems in Parkinson’s disease science Association of diffusion along the perivascular spaces with clinical symptoms and dopaminergic degeneration in Parkinson’s disease science Distinct subthalamic and pallidal beta dynamics in Parkinson’s disease science Common pesticide linked to 2.5 times the risk of Parkinson’s disease science Longitudinal blood-based proteomics reveal progression-specific molecular signatures in Parkinson’s disease science Parkinson’s disease progression and fronto-temporal disconnection relate to identity of minor hallucinations science Nigrosome-1 neuromelanin and iron coupling in idiopathic and GBA-associated Parkinson disease science Spatiotemporally resolved single-nucleus transcriptomics reveals cellular and regional vulnerability in the midbrain in Parkinson’s disease science Microglial NUS1 deficiency drives dopaminergic neurodegeneration through intercellular iron dysregulation in Parkinson’s disease models science Scientists discover a surprising double benefit of exercise for Parkinson’s science USP18 suppresses dopaminergic neuronal ferroptosis in Parkinson’s disease through regulation of SLC7A11 science Cross-cohort exosomal miRNA profiling identifies a robust Parkinson’s disease signature with multi-omics evidence for mitochondrial and immune pathology science Integrative microbiome and functional profiling decodes pro-inflammatory gut microbiome signatures in South Indian patients with Parkinson’s disease science Dysregulated cholesterol trafficking through ABCA1 drives neurodegeneration in Parkinson’s disease science Dopamine amplifies subthalamic long-latency responses to cortical stimulation in patients with Parkinson’s disease science Modeling the heterogeneity of cognitive dysfunction in Parkinson’s disease using partially ordered set models science Reliability and validity of the one-minute sit-to-stand test in Parkinson’s disease science Brain implants are helping people who’ve lost their voice jurnal Gait freezing onset and termination prediction in Parkinson disease using shank sensor acceleration data science A distinct immunometabolic signature defines early-stage Parkinson’s disease with Alzheimer’s disease co-pathology science Clinical, neuroimaging, and longitudinal progression characteristics of GBA1-associated Parkinson’s disease in a Northeast China cohort science A novel eye-tracking oculomotor score correlates with excessive daytime sleepiness and motor progression in Parkinson’s disease science Multi-omics analysis of hypoxia-mitochondrial energy metabolism and programmed cell death profiling in Parkinson’s disease science Author Correction: Parkinson’s disease as a somato-cognitive action network disorder science Striatal network dysfunction underlying speech impairment in early Parkinson’s disease science Impulse control disorder is linked to dyskinesia development through a cortical network in Parkinson’s disease science Drug target could block brain inflammation linked to Alzheimer’s and Parkinson’s science AI-assisted telerehabilitation in early Parkinson’s disease: a multicenter, randomized, multi-arm comparative trial science Bariatric surgery and risk of dementia and Parkinson’s disease in patients with obesity science Disease-specific intrinsic frequency alterations in electroencephalographic signals of Alzheimer’s disease, frontotemporal dementia, and Parkinson’s disease science Cognitive performance before and after a one-week medication washout in early-stage Parkinson’s disease science An explainable EEG connectome framework for frequency-resolved analysis of functional connectivity alterations in Parkinson’s disease science Effects of Nordic walking interventions in Parkinson’s disease, a systematic review, meta-analysis and bibliometric analysis science Alterations of subcortical structures are associated with anxiety in early Parkinson’s disease patients: a cross-sectional 7T MRI study science The impact of nocturnal hypokinesia on supervised and unsupervised mobility in people with Parkinson’s disease science