Week 2 of the 2026 NFL season features 14 Sunday matchups, and NFL bettors are looking for score predictions they can work off of to form spread, total, money-line and prop picks ahead of a massive Week 2 slate. Some notable NFL spreads on the Week 2 NFL schedule include Bengals vs. Texans (-3, 46.5), Steelers vs.
Patriots (-5.5, 41.5), Colts vs. Chiefs (-6.5) on Sunday night and Giants vs. Rams (-7, 48.5) on Monday.
Claim the latest Polymarket promo code CBSSPORTS to get a $50 bonus after $10 in trades: The highest total on the NFL odds board on Sunday is 50.5 in Commanders vs. Cowboys in a key NFC East matchup. Meanwhile, the lowest is 39.5 in Eagles vs.
After losing 23-10 to the Jets at home, Tennessee may face the reality of being in the conversation for the top pick in the 2027 NFL Draft. Before making any Week 2 NFL picks on those games or others, be sure to see the exact Week 2 NFL score predictions from SportsLine's proven model. The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on betting sites on top-rated NFL picks since its inception.
The model enters Week 2 of the 2026 NFL season on a 53-39 run on top-rated picks dating back to 2024. Anybody following its picks at NFL betting sites could have seen strong returns. The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span.
Anyone following at sportsbooks and has seen strong returns at their best sports betting app. Now, the model has simulated every Week 2 game 10,000 times. You can only see the model's Week 2 NFL exact score predictions at SportsLine.
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