College football Week 5 gets rolling with a Conference USA opener on Thursday night as the New Mexico State Aggies host the Western Kentucky Hilltoppers. Western Kentucky (1-3) lost three in a row to start the 2026 college football season before routing FCS Mercyhurst 52-7 last Saturday. The Aggies (1-3) also cruised past Mercyhurst, 51-14, but have losses to Florida State, Hawaii and state rival New Mexico.
We are looking deep into the Western Kentucky vs. New Mexico State odds to highlight some college football bets you can make at top sports betting apps for this C-USA battle. Bet on Western Kentucky vs.
New Mexico State and college football Week 5 at DraftKings and get $150 in bonus bets when you spend $5+: Kickoff is set for 8 p.m. ET on Thursday, Oct. 1 at Aggie Memorial Stadium. The latest Western Kentucky vs.
New Mexico State odds at DraftKings Sportsbook have the Aggies favored by 2.5 points at home, and the Over/Under for total points is set at 55.5. We're providing the Western Kentucky vs. New Mexico State odds and offering insights from the SportsLine Projection Model, which simulates every FBS game 10,000 times.
The model enters Week 5 on a 32-24 run on all top-rated college football picks at the best betting sites, returning nearly $600 for $100 players. Anybody following its picks on college football betting sites could have seen strong returns. The Hilltoppers are hoping an ambitious non-conference schedule puts them in good position heading into Conference USA play.
They faced top national title contender Georgia and reigning national champion Indiana in back-to-back weeks, and it wasn't pretty. The Bulldogs crushed WKU 70-20, then the Hoosiers cruised to a 38-0 victory. The Hilltoppers then gained a little confidence in the win against the FCS Lakers.
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