The Saturday MLB schedule features a critical Al Central matchup as the Detroit Tigers (60-62) host the Chicago White Sox (63-58) in the first matchup of the day. Chicago has a 3.5-game lead over Detroit in the division, while the Tigers enter the day clinging to the final AL wild-card spot by half a game. Lefty Anthony Key (9-5, 3.96 ERA) is on the hill for Chicago, while righty Troy Melton (7-1, 1.46) is starting for Detroit.
Visit our DraftKings promo code review and get $150 in bonus bets instantly as a new user after $5+ in wagers here: First pitch from Comerica Park is set for 1:10 p.m. Detroit is -137 on the money line (risk $137 to win $100), while Chicago is +126. Before making any White Sox vs.
Tigers picks, be sure to see the Tigers vs. White Sox predictions and betting advice from SportsLine's proven computer model. The SportsLine Projection Model simulates every MLB game 10,000 times and entered Week 21 of the MLB season on a sizzling 45-30 run on all top-rated MLB picks.
It also excelled at making home run prop picks in 2025, returning nearly 30 units of profit. Anyone following its MLB betting picks at sportsbooks and on betting sites could have seen strong returns. Now, the model has set its sights on Tigers vs.
White Sox and just locked in its picks and MLB predictions. You can head to SportsLine now to see the model's picks. Here are several MLB odds and betting lines for White Sox vs.
Tigers: After 10,000 simulations of White Sox vs. Tigers, the model is going Over 7.5 combined runs for over/under betting. Chicago has been one of the top Over-producing teams in the league, with 59% of the White Sox's games clearing the total.
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