The 2026 MLB playoffs continue Monday with Game 2 in both ALDS matchups. The early start is Cleveland Guardians vs. Chicago White Sox as Chicago looks to keep its surprising postseason run going.
The White Sox swept the Astros in the wild-card round and then took Game 1 of this series by a 3-0 final. Lefty Anthony Kay (10-9, 4.44 ERA) is set to start for Chicago, while Cleveland turns to righty Gavin Williams (14-8, 3.76 ERA). Claim the latest Polymarket promo code CBSSPORTS to get a $25 bonus after $10 deposit: First pitch from Progressive Field in Cleveland is at 5 p.m.
Cleveland is the -154 favorite (risk $154 to win $100) in the latest Guardians vs. White Sox odds, while the over/under is 6.5 runs. Before making any Guardians vs.
White Sox picks, be sure to see the White Sox vs. Guardians predictions and betting advice from SportsLine's proven computer model. The SportsLine Projection Model simulates every MLB game 10,000 times and entered the divisional round of the 2026 MLB playoffs on a 31-25 run on all top-rated MLB money-line picks at betting sites, returning more than $900 for $100 players.
Anyone following its picks at MLB betting sites could have seen strong returns. Now, the model has set its sights on White Sox vs. Guardians and just locked in its picks and MLB predictions.
You can head to SportsLine now to see the model's picks. Here are several MLB odds and betting lines for Guardians vs. White Sox: New to sports trading?
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