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Ohio State vs. Illinois prediction, odds, time: 2026 Week 4 college football Saturday picks by proven model

Ohio State vs. Illinois prediction, odds, time: 2026 Week 4 college football Saturday picks by proven model

cbssports.com 25.09.2026 16:16 3 views
SportsLine's model has locked in its best bets for the Saturday Big Ten game between the Illinois Fighting Illini and Ohio State Buckeyes

No. 7 Ohio State bounced back from a heartbreaking 24-23 road loss at No. 4 Texas in Week 2 with a 59-3 blowout of Kent State last week behind junior quarterback Julian Sayin. The Buckeyes (2-1) return home to Ohio Stadium on Saturday to face the Illinois Fighting Illini. The Fighting Illini come in at 2-1 as well, picking up their second win of the season with a 48-10 rout of Southern Illinois last week behind senior quarterback Katin Houser, who has put up impressive numbers through three games after a Week 2 loss to Duke.

Claim the latest Polymarket promo code CBSSPORTS to get a $50 bonus after $10 in trades: Kickoff is set for noon ET. at Ohio Stadium in Columbus, Ohio. The Buckeyes are 27.5-point favorites in the latest Illinois vs. The over/under for total points is 53.5.

Before making any Ole Miss vs. Florida picks, check out the Illinois vs Ohio State predictions from the SportsLine Projection Model. The model simulates every FBS game 10,000 times.

It is off to a profitable 22-19 start on all top-rated college football picks at betting sites so far this season, and it has been upgraded for the 2026 season to better factor in the transfer portal. Anybody following its picks on college football betting sites could have seen strong returns. Now, the model has set its sights on Illinois vs.

You can visit SportsLine now to see the picks. Here are the FBS college football odds and trends for Ohio State vs. Illinois: New to sports trading?

Visit our Kalshi promo code review and get a $55 bonus after $25+ in trades with the Kalshi promo code CBSSPORTS55: After simulating Illinois vs. Ohio State 10,000 times, the SportsLine model is going Under (54.5 points) at betting apps. Sayin has shown playmaking ability for the Buckeyes, but a 2-1 Illinois defense that held Southern Illinois to 10 points last week gives the model reason to project a controlled, low-scoring environment at Ohio Stadium rather than a blowout shootout.

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