The Week 1 college football schedule continues throughout Labor Day weekend, with must-see matchups including Oregon vs. Wisconsin and Louisville vs. The only Top 25 matchup this week happens when No. 24 Louisville squares off against No. 9 Ole Miss at Nissan Stadium in Nashville on Sunday at 7:30 p.m.
Claim the newest Kalshi promo code CBSSPORTS, trade $25, and get $25 in trading bonus credits: The updated Week 1 college football prediction market prices are listed below, and SportsLine's advanced computer model has all the college football trading advice and CFB predictions you need to make the best Week 1 college football trades now. The SportsLine Projection Model, which simulates every FBS game 10,000 times, has turned its attention to the latest college football prediction markets and locked in predictions for every CFB matchup. You can also learn how to trade prediction markets and see the latest prediction markets legal states before locking in your college football predictions.
Claim the Underdog Predict promo code CBS and get up to $1,000 in bonus funds here: LSU will kick off its first season under new head coach Lane Kiffin against Clemson in Baton Rouge on Saturday. Kiffin led Ole Miss to its first College Football Playoff berth before accepting the position at LSU, forcing him to miss the postseason. LSU will start former Arizona State quarterback Sam Levitt, who threw for 1,628 yards, 10 touchdowns and three interceptions while being limited to seven games due to injuries in 2025.
LSU's passing attack will also feature junior tight end Trey'Dez Green, who recorded 33 receptions for 433 yards and seven touchdowns last season. Clemson will start redshirt junior Christopher Vizzina at quarterback following Cade Klubnik's departure. Vizzina threw for 406 yards, four touchdowns, and one interception on 45 of 71 passing in five games last season, which included making one start in Klubnik's absence last October.
LSU is trading at $0.77 to win at home, while Clemson is trading at $0.23 at Kalshi. SportsLine is projecting LSU to win, 31-18, on Saturday. Golesh, who went 23-15 in three seasons at South Florida, will take over a team that went 5-7 (1-7 SEC) in 2025.
Former USF quarterback Byrum Brown followed his head coach to Auburn after throwing for 7,690 yards, 61 touchdowns and 19 interceptions in four seasons in Tampa, including 3,158 yards, 28 touchdowns and seven interceptions in 2025. Auburn ranked 10th among SEC teams in total offense (373.9 yards per game), 11th in scoring offense (26.8 points per game), seventh in total defense (329.2 yards allowed per game) and scoring defense (20.7 points allowed per game) last season. Baylor finished the 2025 season with a 5-7 (3-6 Big 12) record.
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