Three teams remain unbeaten on the year as the NFL schedule enters Week 6. Minnesota at 5-0 will remain that way as it is in its bye week. The other unbeatens are in action when the 4-0 Kansas City Chiefs take on the winless Los Angeles Chargers (-8.5) in an AFC West matchup.
The 5-0 San Francisco 49ers will then battle the Washington Commanders (-7.5) on 'Monday Night Football.' Visit our Kalshi promo code review and get a $55 bonus after $25+ in trades with the Kalshi promo code CBSSPORTS55: There are a number of intriguing matchups in Week 6, including Bears vs. Falcons (+3.5) and Steelers vs. Buccaneers (+3) and Cowboys vs.
Packers (-1.5) on 'Sunday Night Football.' Before locking in any Week 6 NFL picks, be sure to see the NFL parlay and betting advice from SportsLine's proven computer model. The model, which simulates every NFL game 10,000 times, is up more than $5,000 for $100 players on betting sites on top-rated NFL picks since its inception. The model entered Week 6 of the 2026 NFL season on a 57-46 run on top-rated picks dating back to 2024.
Anybody following its picks at NFL betting sites could have seen strong returns. Now, the model has scoured the Week 6 NFL odds and locked in five confident NFL best bets. If you successfully parlay its picks, you'd be looking at a massive payout of more than 25-1.
You can only see the model's Week 6 NFL picks at SportsLine. Claim the latest Polymarket promo code CBSSPORTS to get a $25 bonus after depositing $10: After simulating every game 10,000 times, the model is backing the Packers (-113) to defeat the Cowboys as Green Bay wins in 65% of simulations at betting apps on Sunday at 8:20 p.m. The Packers have defeated the Cowboys in eight of the last 10 matchups, including one tie.
That came in last year's meeting, a 40-40 final at AT&T Stadium in Arlington, Texas. Quarterback Jordan Love has been solid this season for Green Bay. In five starts, he has connected on 60.5% of his passes for 1,408 yards and 10 touchdowns with three interceptions.
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