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Week 1 college football predictions, picks for Kalshi, Polymarket: Ole Miss-Louisville, Notre Dame-Wisconsin

Week 1 college football predictions, picks for Kalshi, Polymarket: Ole Miss-Louisville, Notre Dame-Wisconsin

cbssports.com 06.09.2026 15:49 2 views
SportsLine's advanced model has locked in its Week 1 college football predictions from 10,000 simulations

The Week 1 college football schedule features three matchups on Sunday, beginning with Washington vs. Washington State at 4 p.m. ET, followed by Ole Miss vs.

Louisville and Notre Dame vs. The action wraps up on Monday when Florida State squares off against SMU at 7:30 p.m. Claim the newest Kalshi promo code CBSSPORTS, trade $25, and get $25 in trading bonus credits: The updated Week 1 college football prediction market prices are listed below, and SportsLine's advanced computer model has all the college football trading advice and CFB predictions you need to make the best Week 1 college football trades now.

The SportsLine Projection Model, which simulates every FBS game 10,000 times, has turned its attention to the latest college football prediction markets and locked in predictions for every CFB matchup. You can also learn how to trade prediction markets and see the latest prediction markets legal states before locking in your college football predictions. Claim the Underdog Predict promo code CBS and get up to $1,000 in bonus funds here: Louisville will face Ole Miss at Nissan Stadium in Nashville on Sunday evening.

The Cardinals finished their third season under head coach Jeff Brohm with a 9-4 (4-4 ACC) record in 2025, which included winning their final regular season game against Kentucky and the Boca Raton Bowl against Toledo. Louisville will start Lincoln Kienholz at quarterback, making him the fourth transfer player to begin the season under center in four years. Kienholz spent three seasons at Ohio State behind Kyle McCord, Will Howard and Julian Sayin, throwing for 139 yards and one touchdown on 11 of 14 passing in seven appearances last season.

Ole Miss is coming off its best season of the modern era, going 13-2 (7-1 SEC) and making its first College Football Playoff appearance. Pete Golding was named permanent head coach after taking over for a departing Lane Kiffin during the playoffs, which included a Fiesta Bowl loss to Miami in the semifinal. Ole Miss quarterback Trinidad Chambliss threw for 3,937 yards, the most among SEC quarterbacks, 22 touchdowns and three interceptions on 294 of 445 passing, while also recording 527 yards and eight touchdowns on 133 rushing attempts.

Ole Miss is trading at $0.71 to win, while Louisville is trading at $0.29 at Kalshi. SportsLine is projecting the Rebels to win, 33-22, on Sunday. The Badgers finished their third season under head coach Luke Fickell with a 4-8 (2-7 Big Ten) record in 2025.

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