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Alzheimer

60 articles

Blood based multi biomarker panel discriminates Alzheimer disease from healthy controls in a single center nested cross validation science New culprit in early Alzheimer’s: Blood–brain barrier blocks protective proteins science Alzheimer's may have early warning signs outside the brain science Multifunctional phenyl piperidinyl triazoles targeting cholinesterase: toward next-generation Alzheimer's therapeutics science Modulation of cell death and neurogenesis by early intervention with sodium butyrate and galantamine in a streptozotocin-induced Alzheimer's rat model science Two functionally distinct amyloid-β intermediates link aggregation pathways to pathology in Alzheimer's disease science Single-cell machine learning uncovers genetically anchored, cell-type specific programs of Alzheimer's disease science Phase aligned EEG source space features for distinguishing Alzheimer’s disease from frontotemporal dementia science Single-cell and spatial transcriptomics of cellular heterogeneity in Alzheimer disease science Sex and gender bias in the diagnosis of Alzheimer’s disease science Scientists discover mysterious “lonely” brain waves linked to memory loss science Vibrating mattress helps clear Alzheimer’s protein from the brain science Scientists discover new Alzheimer’s drug that repairs DNA damage and reduces brain inflammation science Scientists reverse liver cell aging and cut Alzheimer’s-linked protein in half science A simple blood test could reveal Alzheimer’s risk 10 years before symptoms science Post-stroke cognitive impairment in an Alzheimer’s disease mouse model science A small-molecule TREM2 agonist for Alzheimer’s disease science Hannah Fry: I lost my dad to Alzheimer’s. New research into its origins is amazing science Alzheimer’s disease genetics converges on microglial and neuronal dysregulation science Scientists discover a surprising clue to why some brains resist Alzheimer’s science A pilot cohort study of blood brain barrier permeability in Alzheimer’s disease using dynamic contrast enhanced magnetic resonance imaging science Cholesterol may disrupt the brain’s cleaning system in Alzheimer’s disease science Shuttle systems for delivering antibody therapeutics across the BBB for the treatment of Alzheimer’s disease science Breast carcinoma amplified sequence 2 rescues adult hippocampal neurogenesis and cognitive deficits in Alzheimer’s disease via regulating BDNF/TrkB signaling science Scientists find a way to fight Alzheimer’s brain damage without removing toxic tau science Exploring healthy aging through preclinical Alzheimer disease in the Knight Alzheimer Research Imaging dataset science Emotional valence and musical factors associated with music-evoked memories in Alzheimer’s disease science EEG-based Alzheimer’s disease detection using two-branch multi-scale deep learning with integrated gradients-guided channel selection science Why some people escape Alzheimer’s despite carrying a high-risk gene science "Mind-blowing" Alzheimer’s breakthrough: Two hours of sleep restored without clearing brain plaques science A cell-based multivariate blood test (iCAP) for early detection of Alzheimer’s disease capturing non-amyloid-β biology science APOE ε4 carriership status enhances age-related changes in Alzheimer’s disease plasma biomarkers concentrations science Dietary elimination of gluten attenuates amyloid-β and tau pathology in Alzheimer’s disease-like in aluminum chloride-induced rats: an experimental animal study science Rare study reveals a striking divide inside an Alzheimer’s patient’s brain science A distinct immunometabolic signature defines early-stage Parkinson’s disease with Alzheimer’s disease co-pathology science Scientists may have overlooked a hidden Alzheimer's culprit for decades science Exploring PET and MRI brain networks across healthy controls, mild cognitive impairment, and Alzheimer’s disease science Scarred blood vessels may be one clue to APOE4’s Alzheimer’s risk jurnal Genome-wide analysis of common structural variants in Alzheimer’s disease identifies a risk-associated regulatory CCG repeat in FAM193B science Serine-65 phosphorylated ubiquitin associates with soluble tau and seeding activity in Alzheimer’s disease science The hidden math of Alzheimer's could point to new treatments science Suppression of follistatin by spontaneous seizures dysregulates neurogenesis in a model of Alzheimer’s disease neuropathology science Higher plasma oleic acid is associated with slower progression from mild cognitive impairment to Alzheimer’s disease in men and women science APOE2 attenuates APOE4-associated amyloid pathology and related toxicity in a mouse model of Alzheimer’s disease science Single-cell, spatial, and machine learning analyses identify ANKIB1 as an oligodendrocyte-anchored palmitoylation-associated candidate biomarker of Alzheimer’s disease science Drug target could block brain inflammation linked to Alzheimer’s and Parkinson’s science SPLASH: a benchtop platform for accessible, ultrasensitive quantification of plasma biomarkers in Alzheimer’s disease science Why Do Obese People With Alzheimer’s Live Longer? jurnal Multimodal patch-based deep learning for early Alzheimer’s disease classification using MRI and PET science Disease-specific intrinsic frequency alterations in electroencephalographic signals of Alzheimer’s disease, frontotemporal dementia, and Parkinson’s disease science Efficient deep learning models for early Alzheimer’s disease diagnosis science Alzheimer’s disease neuropathological characterization of the dog brain and relationship to biofluid biomarkers and cognitive function science Can we harness the brain’s deep-cleaning system to prevent Alzheimer’s? science An uncertainty-aware multimodal deep learning framework for Alzheimer’s disease classification using MRI and electronic health records science An effective and deep learning model to predict Alzheimer’s disease at an early stage from audio data science Burnham’s plans for social care and its workers are admirable but changes must come quickly | Heather Stewart politics Your gut may be making a molecule that raises Alzheimer’s risk science Golgi dysfunction in Alzheimer disease: from human multiomic signatures to therapeutic targets science An integrative single-cell genetic analysis prioritizes immune cell-specific genes and drug repurposing hypotheses in Alzheimer’s disease science A model of brain function to predict tau across Alzheimer’s disease and related disorders science